Algae-Based Gel Offers Tunable Environment for Breast Cancer Research
Scientists from the University of Cambridge and the University of Queensland have developed an innovative algae-based gel. This gel, capable of supporting normal mammary tissue, offers a modifiable environment to control cell growth direction. The research, published in Science Advances, aims to advance our understanding of breast cancer progression and engineered tissue formation.
The gel's response to force can be tuned by adjusting polymer chain length and crosslinking. This allows researchers to mimic different stages of tumor development by modifying the gel's stiffness. The gel's mechanical and biochemical properties can also be adjusted to control cell growth and behavior, providing valuable insights into how different matrices contribute to cell development.
The gel's capabilities match those of Matrigel, a commercially available gel for studying mammary cells. However, it offers the advantage of being modifiable, allowing researchers to guide the formation of functional engineered tissues. The study's authors hope to uncover insights into guiding the formation of functional engineered tissues by applying an engineering approach to developmental biology. Ultimately, the goal is to use the gel to grow complex tissues and organs from patient cells.
The algae-based gel, developed by researchers at UCSB, presents a promising tool for studying mammary epithelial morphogenesis and invasion. By offering a tunable and modifiable environment, it could significantly advance our understanding of breast cancer progression and engineered tissue formation. The gel's potential to grow complex tissues and organs from patient cells opens up exciting possibilities for regenerative medicine.
Read also:
- FDA's Generic Mifepristone Approval Sparks Pro-Life Concerns Over Safety and States' Rights
- Understanding Child Development: Causes and Signs of Delays
- Top Superfoods for Hormonal Health: Avocados, Berries, Flaxseeds, Turmeric, and Cruciferous Veggies
- Pope Francis' New Book 'Let Us Dream' Offers Unity and Hope for Post-Covid World
