How boosting autophagy could slow aging and fight disease
Autophagy is a natural process where cells break down and recycle damaged parts. This mechanism plays a key role in keeping cells healthy and slowing down ageing. Scientists have uncovered ways to boost it through lifestyle and diet.
The process was first explained in detail by Yoshinori Ohsumi, whose work revealed its importance in ageing and diseases like Alzheimer’s and Parkinson’s. Later, researchers at the Institute for Molecular Biology in Mainz, including Thomas Wilhelm and Dr. Holger Richly, found that adjusting certain autophagy genes in older organisms could extend their lifespan.
Autophagy helps remove faulty cellular components, which build up as we age. Staying hydrated supports this process, as water is vital for cell function. Getting enough quality sleep also keeps autophagy running smoothly.
Several lifestyle habits can trigger autophagy. Intermittent fasting and caloric restriction both activate the process, helping cells stay efficient. A ketogenic diet has a similar effect by shifting how the body uses energy. Regular exercise is another way to stimulate autophagy naturally.
Foods rich in phytochemicals—like berries, leafy greens, and spices—can also support the process. These compounds help cells clear out damage more effectively.
The findings highlight how simple changes in diet and routine can enhance autophagy. By removing damaged cell parts, the process helps slow ageing and reduce disease risk. Researchers continue to explore how these strategies could improve long-term health.
