How diabetes medications impact weight gain and loss differently
Diabetes treatments vary widely in their effects on body weight. Some medications can lead to weight gain, while others may help with weight loss or remain neutral. Understanding these differences is key for patients managing both blood sugar and weight.
Certain antihyperglycemic drugs are known to cause weight gain. Thiazolidinediones (TZDs) like pioglitazone and rosiglitazone can add between 3.3 and 8.8 pounds (1.5 to 4 kilograms) in the first year. Sulfonylureas, including glimepiride, glipizide, and glyburide, may also result in a gain of up to 8.8 pounds (4 kilograms) during the same period. Other medications linked to weight gain include chlorpropamide, gliclazide, insulin, repaglinide, and tolbutamide.
Choosing the right diabetes medication involves balancing blood sugar control with weight management. Patients should discuss their options with a doctor to find the most suitable treatment. A personalized plan, along with lifestyle adjustments, can help achieve better overall health outcomes.
