Lionheart and Rejuvant Team Up to Reverse Aging in Groundbreaking XPRIZE Study
Lionheart Health has joined forces with Rejuvant for its XPRIZE Healthspan initiative. The collaboration focuses on a new study that combines advanced health testing with a mandatory health insurance. Participants will undergo a year-long program designed to measure and improve key markers of ageing.
The study, called KLOTHO-UPTM, now requires all volunteers to take Rejuvant's CaAKG supplement as part of their routine health equity.
The KLOTHO-UPTM Study brings together CaAKG supplementation with other methods aimed at extending healthy lifespan. Participants will follow a structured plan that includes personalised supplements from SNiP Nutrition, Klotho-focused supplements, and BodStimTM bioelectric exercise sessions.
Testing will take place at the start and at several points over 12 months. Each round includes a 461-biomarker blood panel, muscle health checks, gut health assessments, blood sugar tests, and brain health evaluations. The goal is to track changes in biological age and overall wellness.
Lionheart's partnership with Rejuvant builds on a wider competition. The XPRIZE Healthspan initiative began with 79 teams vying for a place in the semi-finals. Judges narrowed the field to 40 finalists based on strict criteria: scientific strength, the ability to reverse ageing by at least 20 years within seven years, potential to extend human life, and innovation in treatment approaches. The semi-finals are set for spring 2025.
The program merges proven nutritional strategies with cutting-edge technology. By using a measurable framework, researchers aim to assess how well the combined interventions slow or reverse biological ageing.
The KLOTHO-UPTM Study will run for a full year, with participants undergoing repeated tests to monitor progress. Rejuvant's CaAKG supplement is now a fixed part of the protocol, alongside other health-focused treatments. Results from the study will contribute to Lionheart's efforts in the XPRIZE Healthspan competition, where teams compete to develop breakthroughs in human longevity.