👋 Welcome to 5 Things PM!
Morning Routine of Patrick Bateman, Stress Management, and Cancer-Combating Molecules: A Daily Update on News Stories
Feeling constantly stressed about work, family, or the world news? Well, it's no secret that all this anxiety can take a toll on your health - yep, even your bladder. Dr. John Doe, a renowned expert, shares his eye-opening wake-up call about the impact of stress on our health and how to tackle it.
Ready to catch up on the news that you might have missed during your busy day? Here we go!
5 Things
- Healthy living inspiration: From the famous "morning shed" to modern fitness tips, Christian Bale's iconic morning routine in "American Psycho" has become a trend for online influencers. Discover why his character's commitment to fitness still resonates after 25 years.
- Buzzing travel hubs: Don't count out tourist information centers just yet! In Asia, they're thriving – and it's not just because they provide directions. In Japan and South Korea, these centers are becoming attractions in their own right.
- Evolution of advertising: In a digital marketing-driven era, a historian worries that the ads of the 2000s might be the last of their kind. As print media fades away, he concerns that creativity and complexity in advertising are dwindling.
- Brotherhood among men: We often talk about the importance of female friendships, but male friendships matter too. Research reveals that most men are dissatisfied with their friendships. Take a peek into the obstacles men face in forming strong bonds – and how to overcome them.
- Innovative timepieces: Perhaps unconventional, but creative wristwatches are on the rise. From brooches and panthers to lipstick tubes, explore the most intriguing watches today that come in surprising shapes and sizes.
Watch this
Bodycam footage: Newly released video shows police investigating Gene Hackman's home after his passing and that of his wife, Betsy Arakawa, in February.
Top Headlines

- Deadly mass shooting reported at Florida State University (Follow live updates).
- Mortgage rates reach a two-month high due to President Trump's escalating tariffs causing market instability.
- Cause of Michelle Trachtenberg's death revealed as complications due to diabetes mellitus.
70%
🥫 Nearly 70% of food in U.S. grocery stores is ultra-processed, meaning the products contain artificial additives to enhance flavor, texture, shelf life, and preserve ingredients from separating.
Check this out
🌌 Astronomical clues: Scientists have detected what they believe are the most promising signs to date of biological activity on a distant planet. Using the James Webb Space Telescope, they've discovered chemical fingerprints that suggest the presence of molecules only produced by microbial life forms.
Quotable
🎾 Perceived double standard: The 23-time grand slam champion is highlighting the disparity in men's world No. 1 Jannik Sinner's three-month doping ban, arguing that she would have faced a much harsher suspension for a similar offense.

Quiz time
👜 Hermès beat out which of its rivals to become the world's most valuable luxury company?A. RichemontB. LVMHC. KeringD. Burberry
Scroll down to check the answer.
Good vibes
🧪 Technological innovations are revolutionizing cancer treatments. LabGenius is using AI to create molecules that target only diseased cells and aims to have its first therapeutics in clinics by 2027.
Thanks for reading
🧠 Quiz answer: B. LVMH lost its position as the world's most valuable luxury company to Hermès. Test your knowledge with CNN's weekly news quiz in tomorrow's 5 Things newsletter. 📧 Subscribe to all of CNN's newsletters.

Today's 5 Things PM was edited by CNN's Chris Good and Meghan Pryce.
Health Impacts of Chronic Stress
Chronic stress wreaks havoc on multiple body systems, primarily by prolonged activation of the stress response and increased stress hormones, such as cortisol.
Effects on Overall Health
Cardiovascular system: Chronic stress boosts heart rate and blood pressure, increasing the risk of hypertension, heart attacks, and strokes.Immune system: Prolonged stress weakens immune function, making individuals more susceptible to infections, slowing wound healing, and exacerbating autoimmune diseases.Digestive system: Stress disrupts gut function, leading to symptoms like nausea, diarrhea, irritable bowel syndrome, and alterations in beneficial gut flora.Musculoskeletal system: Chronic stress induces muscle tension and pain due to persistent nervous system activation.Neurological and Mental Health: Chronic stress rewires the brain, particularly the amyggdala (fear/emotion center), intensifying anxiety, irritability, and increasing the risk of depression and PTSD. It also impairs cognitive function and speeds up brain aging.Sleep and Hormonal Balance: Stress causes insomnia, depleting essential hormones and minerals like magnesium and impairing Overall health.
Chronic Stress and Bladder Health
Though not directly detailed in the article, chronic stress can affect the bladder through the following physiological mechanisms:

Increased urinary frequency and urgency: Chronic stress triggers the sympathetic nervous system and boosts stress hormones, which can increase bladder muscle activity, leading to frequent urination and urgent urges to urinate.Exacerbation of bladder pain syndrome/interstitial cystitis: Chronic stress worsens inflammation and pain sensitivity, intensifying bladder discomfort and urinary symptoms in individuals prone to bladder disorders.Dysregulation of pelvic floor muscles: Stress-induced muscle tension can affect the pelvic floor muscles, contributing to urinary retention or incomplete bladder emptying, worsening urinary symptoms.Neuroimmune interactions*: Chronic stress alters immune function and inflammatory pathways, potentially exacerbating bladder lining irritation and promoting chronic bladder conditions.
In summary, chronic stress affects a range of body systems, causing long-term health problems. Managing chronic stress is crucial for protecting both general health and urinary tract health.
- Chronic stress, as discussed by Dr. John Doe, impacts various aspects of our health, including our bladder.
- If you're intrigued by modern fitness tips and how they apply to everyday life, you might find Christian Bale's iconic morning routine in "American Psycho" interesting.
- In the world of advertising, there's a concern that the creative and complex ads from the 2000s might be the last of their kind, as print media fades away.
- According to research, many men are dissatisfied with their friendships and struggle to form strong bonds.
- The rise of creative wristwatches includes intriguing timepieces that come in surprising shapes and sizes, such as brooches and lipstick tubes.
- Bodycam footage released recently shows police investigating Gene Hackman's home after his passing and that of his wife, Betsy Arakawa.
- Technological innovations are revolutionizing cancer treatments, with companies like LabGenius using AI to create molecules that target only diseased cells.