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Semaglutide’s weight loss benefits fade after stopping treatment

The promise of rapid weight loss fades fast—what happens when the injections stop? Experts warn of rebound without lifestyle changes.

In this image I can see there are exercise cycles. Few people are doing workout on them, they wore...
In this image I can see there are exercise cycles. Few people are doing workout on them, they wore white color t-shirts, at the bottom there is the bag. On the left side there is a tree.

Semaglutide’s weight loss benefits fade after stopping treatment

Semaglutide, a drug used in medications like Wegovy, Ozempic, and Rybelsus, has gained attention for its role in weight loss. While Wegovy is the only version officially approved for this purpose in the U.S., many people also use Ozempic and Rybelsus off-label. However, stopping the treatment often leads to weight regain, raising questions about long-term effectiveness.

Semaglutide works by suppressing appetite and increasing feelings of fullness. As a glucagon-like peptide-1 (GLP-1) receptor agonist, it also helps balance blood sugar levels. Wegovy is FDA-approved for weight loss and reducing cardiovascular disease risk, while Ozempic and Rybelsus are primarily prescribed for managing type 2 diabetes.

Semaglutide offers a way to lose weight, but its effects often fade after stopping the drug. Those looking for lasting results may need to pair it with ongoing support from healthcare professionals and healthy habits. Without these steps, weight regain remains a common challenge for many users.

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